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J Occup Health year 2002 volume 44 number 4 page 226 - 229
Classification Original
Title Effects of Electromagnetic Field on Free-Radical Processes in Steelworkers. Part I: Magnetic Field Influence on the Antioxidant Activity in Red Blood Cells and Plasma
Author Boguslaw KULA1, Andrzej SOBCZAK2 and Rafal KUSKA3
Organization 1Department of Experimental and Clinical Biochemistry, Silesian School of Medicine
2Department of General and Analytical Chemistry, Silesian School of Medicine and
3Department of Medical Biophysics, Silesian School of Medicine, Poland
Keywords Electromagnetic field, SOD, CAT, GSH-Px, MDA, Ceruloplasmine
Correspondence A. Sobczak, Department of General and Analytical Chemistry, Silesian School of Medicine, Jagiellonska 4, Sosnowiec 41-200, Poland
Abstract Effects of Electromagnetic Field on Free-Radical Processes in Steelworkers. Part I: Magnetic Field Influence on the Antioxidant Activity in Red Blood Cells and Plasma: Boguslaw KULA, et al. Department of Experimental and Clinical Biochemistry, Silesian School of Medicine, Poland-The purpose of the study was the evaluation of electromagnetic field (electric field strength of 20 V/m, f=50 Hz and magnetic field strength of 2 A/m, f=50 Hz) effects on the antioxydative activity in steelworkers' red blood cells and plasma. The plasma GSH-Px (EC 1.11.1.9) activity, MDA and ceruloplasmin levels as well as SOD (EC 1.15.1.1.), CAT (EC 1.11.1.6) and GSH-Px (EC 1.11.1.9) in red blood cells were measured. Statistically significant decreases in red blood cells SOD and GSH-Px activities, a CAT activity increase and plasma MDA increase and a ceruloplasmin decrease were found in workers exposed for 3-10 yr and for longer than 10 yr to electromagnetic fields. No statistically significant changes in the parameters evaluated were found among steelworkers employed for shorter than 3 yr. All changes observed among workers exposed to electromagnetic fields result in adaptative responses by activating systems controlling the balance of body oxidative mechanisms.