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J Occup Health year 2007 volume 49 number 5 page 382 - 388
Classification Original
Title A Prospective Cohort Study of Perceived Noise Exposure at Work and Cerebrovascular Diseases among Male Workers in Japan
Author Yoshihisa Fujino1, Hiroyasu Iso2, Akiko Tamakoshi3, for the JACC study group4
Organization 1Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Japan, 2Public Health, Department of Social and Environmental Medicine, Graduate school of Medicine, Osaka University, 3Department of Epidemiology, National Institute for Longevity Sciences, 4See acknowledgments for the investigators (name and affiliation) involved in the JACC Study, Japan
Keywords Cerebrovascular disorders, Cohort studies, Japan, Noise, Stress
Correspondence Y. Fujino, Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Japan, 11 Iseigaoka, Yahatanishiku, Kitakyushu 8078555, Japan (e-mail: zenq@med.uoeh-u.ac.jp)
Abstract A Prospective Cohort Study of Perceived Noise Exposure at Work and Cerebrovascular Diseases among Male Workers in Japan: Yoshihisa Fujino, et al. Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Japan- This study prospectively examined the association between perceived noise exposure at work and cerebrovascular diseases among Japanese male workers. A baseline survey was conducted between 1988 and 1990, which involved 110,792 inhabitants (age range: 40-79 yr) from 45 areas throughout Japan. Subsequent causes of death were identified from death certificates. The analysis was restricted to 14,568 men free of a cerebrovascular diseases (age range: 40-59 yr) who were in work at the time of the baseline survey. All subjects completed a self-administered questionnaire at the baseline. This included a question regarding perceived noise exposure at work. The Cox proportional-hazards model was used to estimate the risks of perceived noise exposure for death due to cerebrovascular diseases. The model included age, smoking, alcohol consumption, educational level, perceived mental stress, past medical history, body mass index, hours of walking, hours of exercise, shift work, and job type. During the 190,777 person-years of follow-up, a total of 1,064 deaths were recorded, 98 from cerebrovascular diseases, 27 deaths from subarachnoid haemorrhage, 35 deaths from intracerebral haemorrhage, and 25 deaths from cerebral infarction. Noise exposure did not increase the risk of cerebrovascular diseases, subarachnoid haemorrhage, or cerebral infarction. However, perceived noise exposure increased the risk of intracerebral haemorrhage diseases (hazard ratio (HR)=2.38, 95%CI: 1.20, 4.71, p=0.013). Furthermore, individuals with hypertension were highly susceptible to the effect of perceived noise exposure on the risk of intracerebral hemorrhage, but this association was not observed among the subjects without hypertension. Although the underlying mechanisms are not clear, hypertensive individuals with perceived noise exposure at work should be regarded as a high-risk group for intracerebral hemorrhage.